1. MUMmer
MUMmer is a bioinformatics software system for sequence alignment. It is based on the suffix tree data structure and is one of the fastest and most efficient systems available for this task, enabling it to be applied to very long sequences. It has been widely used for comparing differen...
标签:Genomics,推荐,比较基因组
2. Maq
Mapping and Assembly with Qualities (renamed from MAPASS2). Particularly designed for Illumina-Solexa 1G Genetic Analyzer, and has preliminary functions to handle ABI SOLiD data. Maq stands for Mapping and Assembly with Quality. It builds assembly by mapping short reads to reference ...
标签:Genomics, SNP discovery
3. Mauve
Mauve Genome Alignment software, for comparing two or more draft or finished genomes
标签:Genomics, Transcriptomics
4. MEGAN
Metagenome Analysis Software - MEGAN (“MEtaGenome ANalyzer”) is a new computer program that allows laptop analysis of large metagenomic datasets. In a preprocessing step, the set of DNA reads (or contigs) is compared against databases of known sequences using BLAST or another compar...
标签:Metagenomics
5. MG-RAST
MG-RAST is a fully-automated service for annotating metagenome samples providing analysis tools for comparison
标签:Metagenomics, Phylogenetics,Metabolic reconstruction
6. PyroNoise
Clustering of pyrosequencing (454) data with noise model (AmpliconNoise) and chimaera removal (Perseus) for sequence diversity analysis.
标签:Phylogenetics, Metagenomics
7. seqmonk
A tool to visualise and analyse high throughput mapped sequence data SeqMonk is a program to enable the visualisation and analysis of mapped sequence data
标签:Genomics, Epigenomics
8. BEDTools
BEDTools is an extensive suite of utilities for comparing genomic features in BED format. A powerful toolset for genome arithmetic.
标签:Genomics
9. IGV
The Integrative Genomics Viewer (IGV) is a high-performance visualization tool for interactive exploration of large, integrated datasets. It supports a wide variety of data types and format, including short-read alignments in the SAM/BAM format. Data can be viewed from local files or ov...
标签:Genomics
10. MrFAST
mrFAST is designed to map short reads generated with the Illumina platform to reference genome assemblies; in a fast and memory-efficient manner.
标签:Genomics
11. BiQ Analyzer
BiQ Analyzer is a software tool for easy visualization and quality control of DNA methylation data. With more than 2,000 downloads so far, BiQ Analyzer has become a standard tool for processing DNA methylation data from bisulfite sequencing.
标签:Epigenomics, DNA methylation
12. ANNOVAR
ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data
标签:Genomics, Genetics
13. ERGO Genome Analysis and Discovery System
ERGO provides a systems-biology informatics toolkit centered on comparative genomics to capture, query and visualize sequenced genomes. Building upon the most comprehensive genomic database available anywhere integrated with the largest collection of microbial metabolic and non-metaboli...
标签:Metabolic reconstruction,Phylogenetics, Comparative genomics, SNP Annotation, SNP discovery, Alignment, Exome analysis, Metagenomics,Pathway analysis, Comparative transcriptomics, Functional Genomics, Gene Expression Analysis, Genome Wide Association Stud
14. BreakDancer
BreakDancer is an application for detecting structural rearrangements and indels in short read sequencing data BreakDancer, released under GPLv3, is a Cpp package that provides genome-wide detection of structural variants from next generation paired-end sequencing reads. It include...
标签:Genomics, Structural variation, InDel discovery
15. CLCbio Genomics Workbench
De novo and reference assembly SNP and small indel detection and annotation.
标签:Genomics, Whole Genome Resequencing, De-novo assembly, SNP discovery, InDel discovery, ChIP-Seq, RNA-Seq,MiRNA, Transcriptomics
16. SeqMan NGen
Sequence assembly software using traditional, next-gen, and third-gen techonologies. Subsequent analysis of the assembly, including SNP discovery, coverage evaluation and consensus annotation is provided through full integration with Lasergene.
标签:Genomics, De-novo assembly, De novo transcriptome assembly,Whole Genome Resequencing, SNP discovery, InDel discovery,ChIP-Seq, RNA-Seq Alignment
17. Tablet
Tablet is a lightweight, high-performance graphical viewer for next generation sequence assemblies and alignments. Tablet is a lightweight, high-performance graphical viewer for next generation sequence assemblies and alignments. Tablet is a lightweight, high-performance graphical...
标签:Genomics, Genotyping,Comparative genomics
18. MetaSim
The software can be used to generate collections of synthetic reads. Générateur de reads ou de mate-pairs à partir d’un modèle d’erreur de séquençage adaptable (Sanger, 454 ou Illumina) et d’une base de données. Générateur de reads ou de mate-pairs à partir d’un modèle d’erreur de...
标签:Metagenomics, Genomics
19. Phymm
A classifier for metagenomic data, that has been trained on 539 complete, curated genomes and can accurately classify reads as short as 100 base pairs
标签:Metagenomics
20. SICER
A clustering approach for identification of enriched domains from histone modification ChIP-Seq data.
标签:ChIP-Seq, Epigenomics